CRISPR is a gene editing technique with incredible potential. But the traditional CRISPR-Cas9 approach involves cutting the double helix of DNA in cells, which can have many unintended and dangerous ...

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes. However, this process is associated with side effects including unwanted mutations ...

A Penn State-led team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020. While CRISPR ...

A powerful new approach for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes—which are commonly used to build drug molecules—has been developed. The ...

In a major step toward treating rare neurological diseases, scientists have used gene editing to correct mutations inside the brain of living mice with a single injection. This new approach, described ...

Oct. 29 (UPI) --Researchers testing technology to edit DNA during human development -- with the hope of preventing disease -- have found that the process often eliminates an entire section of genetic ...

A research team led by scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) has introduced a new way to fine-tune genetic material. Their study, published in Nature ...

PHILADELPHIA— A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach ...

The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment of diseases. However, existing genome editing ...

Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature ...