As sponsors advanced more niche and personalized modalities, manufacturers were pushed to adopt holistic approaches to safety ...

Insights into molecular behaviors and predictive capabilities are bringing numerous benefits. The potential benefits afforded by molecular modeling when applied to formulation development are, in fact ...

Formulation scientists are behind the conversion of active pharmaceutical ingredients (API) into stable, bioavailable, and commercially viable dosage forms, rarely a simple process. Image Credit: ...

To optimize the final formulation for a drug, it must meet many criteria beyond producing a safe and effective product. For example, it must be stable and amenable to various manufacturing steps, such ...

How integrated pharmaceutical manufacturing helps CDMOs simplify scale-up, reduce complexity, and move from raw materials to finished dosage forms faster.

Early on, the drug substance (DS) manufacturer will provide a wealth of preliminary characterization data. And if the drug is active in early nonclinical and preclinical testing, a larger quantity of ...

Researchers at the University of Toronto say they have successfully tested the use of machine learning models to guide the design of long-acting injectable drug formulations. The potential for machine ...

The pharmaceutical excipients market is undergoing a transformative phase, becoming an increasingly essential component in drug formulation. According to market insights from Future Market Insights ...

Fizzy drug formulations may pose CV risk Taking effervescent medication on a regular basis may increase patients' risk for cardiovascular events due to excess sodium. Effervescent, dispersible and ...

The media have been replete with reports of ways in which the pharmaceutical industry has been able to increase revenue from medications that have been available for decades. 1 We report a new ...