A senior FDC official said the product is a “failed therapy” and confirmed that regulators have asked uniQure to run a new ...

In a strikingly blunt briefing, a senior FDA official accused uniQure of pushing “distorted” data to mask a “failed” therapy ...

An international, randomized, double-blind, placebo-controlled Phase III study—the largest of its kind for mpox—found that tecovirimat did not improve clinical outcomes for adults with clade II mpox ...

Utility of the 70-Gene MammaPrint Assay for Prediction of Benefit From Extended Letrozole Therapy in the NRG Oncology/NSABP B-42 Trial Patients with advanced lung cancer reporting at least moderate ...

A randomized trial of hospitalized patients with moderate hyponatremia compared targeted sodium correction versus routine care on mortality and rehospitalization rates.

Malaria control and elimination is threatened by the spread of insecticide resistance and behavioral adaptation of vectors. Whether mass administration of ivermectin, a broad-spectrum antiparasitic ...

However, traditional clinical trial designs are often ill-suited for rare disease research with common challenges including ...

Researchers at The Hospital for Sick Children (SickKids), working with international collaborators and youth and family ...